Welcome to the histology home page!

This course explores microanatomy and the many fascinating links between form and function at the microscopic level. To be successful in the M2 pathology course, you must be able to recognize and understand the function of normal cells and tissues. This is the main objective of this course.

The major components of this course are: 1) textbook reading assignments ("Basic Histology", 11th Edition, by Junqueira and Carneiro; MacGraw-Hill Medical Publishing Division), 2) web-based laboratory excercises, 3) small group lab meetings during which you will use microscopes to look at tissue sections, and 4) course lectures.

You are expected to have completed the reading assignments BEFORE coming to lecture. Lectures will amplify and extend some of the material covered in the reading assigments.

News:

Posted/Modified on Thursday April 16th:
Histology Final exam will consist of multiple choice questions divided among the lectures/labs starting with Liver on Jan. 20th. The focus will be identification of structure and some structure function. All questions will have photos of tissues that you must recognize. Some questions will ask you to compare organs; i.e., which of the following is liver? Which of the following is thyroid? There will be no electron micrographs. There will be low mag photos along with high mag photos when needed; i.e., low mag liver photo along with the high mag that shows a bile duct. To assist you in studying for this exam, I made a list of all required structures, which is found at the following URL: http://vetmed.illinois.edu/~rexhess/medhisto/final2009.pdf

Posted/Modified on Friday February 27th:
Histology II progress exam March 6 will consist of 20 multiple choice questions. The exam will cover Liver, pancreas, oral cavity & associated structures, gastrointestinal tract, hypophysis and hypothalamus, pituitary, endocrine glands and urinary system. The following is an example question: Which statement regarding the liver is true? A. Hepatocytes have an abundance of cilia to stir the fluid in the space of Disse. FEEDBACK: there are no cilia B. Portal vein blood has higher oxygen than the hepatic artery. FEEDBACK: no, the hepatic artery is oxygenated C. Hepatic artery opens into the central venule. FEEDBACK: no, opens into the sinusoids jointly with the portal venules D. Central veins (venules) collect blood drained from the hepatic sinusoids. FEEDBACK: yes

Posted/Modified on Tuesday February 24th:
Notes regarding Kidney. There have been some minor changes in wording regarding the nephron tubules. Toxicology has found that specific chemicals can target specific regions of the tubular system and therefore the labeling of the tubules has changed regarding the thick limbs of Henle (see my lecture slides). The literature remains mixed, with some still calling them the "descending thick limbs and the ascending thick limbs of Henle". However, these regions do not function like the thin limb and the thick regions do not extend into the medulla. Therefore, the new names are "Proximal Straight and Distal Straight tubules." Here is the new sequence: Proximal convoluted tubules-- proximal straight- thin limb of Henle -- distal straight -- distal convoluted. Glomeruli that are located high in the cortex do not even form thin limbs and the proximal straight tubule will loop back in the juxtamedullary region to form the distal straight. The thin limbs are purely squamous epithelium that help to maintain the high salt concentration in the medulla. Their squamous cell nuclei are larger than the squamous cells of the endothelium in the vasa recta and the nuclei bulge into the tubule lumen.

Posted/Modified on Tuesday November 4th:
You can find the Practice Histology I Final Exam by going to On-line Exams (Bluestem login required) and then scrolling down to the Histology heading. To start the exam, enter the exam password (which is "password") and click on the "Begin" button. After your first practice exam session has ended, you will be able to go back over the practice exam again as many times as you want to. During these subsequent sessions, you will be given feedback for incorrect responses. My recommendation is to take advantage of this feedback. It can help guide you to important concepts.

Posted/Modified on Tuesday November 4th:
Here are the study guides for the first and second progress exams. These are definitely useful and relevant when preparing for the HIstology I final exam. The Final Exam Study Questions and Study Guide should also help focus your study on the most important material.

©  1999 Benjamin D. Williams, Ph.D., Aulikki Kokko-Cunningham, M.D., Steven Cvetko, Ph.D, Richard Mintel, Ph.D., and the Board of Trustees of the University of Illinois at Urbana-Champaign. All rights reserved.